Health Status and Quality of Life in Patients With Early Stage Hodgkin's Disease: A Companion Study to SWOG-9133
OBJECTIVES: I. Evaluate prospectively the health status and quality of life of patients with
Stage I/IIA Hodgkin's disease randomized on protocol SWOG-9133 (CLB-9391) to treatment with
subtotal nodal irradiation with vs. without 3 courses of doxorubicin/vinblastine. II.
Describe the short-term effects of these treatments on these patients and compare their
impact on quality of life (i.e., patient symptom status, health status, fatigue). III.
Evaluate the intermediate and long-term effects of these treatments on these patients and
compare their impact on quality-of-life outcomes over 5 years.
OUTLINE: Quality-of-Life Assessment. Cancer Rehabilitation Evaluation System Short Form,
CARES-SF; Symptom and Personal Information Questionnaire (including Symptom Distress Scale,
MOS SF-36 Fatigue Scale, MOS SF-36 Health Perception Rating, Demographics); Cover Sheet.
PROJECTED ACCRUAL: Approximately 500 patients will be accrued over 7 years.
Observational Model: Case-Only, Time Perspective: Prospective
Patricia A. Ganz, MD
Jonsson Comprehensive Cancer Center
United States: Federal Government
|Roswell Park Cancer Institute||Buffalo, New York 14263|
|Walter Reed Army Medical Center||Washington, District of Columbia 20307-5000|
|University of Iowa Hospitals and Clinics||Iowa City, Iowa 52242|
|University of Massachusetts Memorial Medical Center||Worcester, Massachusetts 01655|
|Comprehensive Cancer Center of Wake Forest University Baptist Medical Center||Winston-Salem, North Carolina 27157-1082|
|Rhode Island Hospital||Providence, Rhode Island 02903|
|Ellis Fischel Cancer Center - Columbia||Columbia, Missouri 65203|
|Barnes-Jewish Hospital||Saint Louis, Missouri 63110|
|State University of New York - Upstate Medical University||Syracuse, New York 13210|
|University of Tennessee, Memphis Cancer Center||Memphis, Tennessee 38103|
|Beth Israel Medical Center||New York, New York 10003|