Inclusion Criteria

Inclusion Criteria

Concurrent Medication:

Allowed:

- Maintenance antihormones, hormones, and glucocorticoids.

Patients must have:

- Histologically proven metastatic cancer including Kaposi's sarcoma and
lymphoproliferative disorders to the skin or cutaneous sites. NOTE:

- Primary basal or squamous cell cancer of the skin is allowed.

- Failed both primary and secondary chemotherapy and/or immunotherapy protocols.

- Measurable skin or cutaneous lesions. 4 Life expectancy of at least 20 weeks.

Prior Medication:

Required:

- Prior therapy for cutaneous lesions from Kaposi's sarcoma or lymphoproliferative
disorders.

Allowed:

- Prior maintenance steroids and hormone/antihormone therapy.

Exclusion Criteria

Co-existing Condition:

Patients with the following symptoms or conditions are excluded:

- Active infections other than medically stable HIV infection.

- Active congestive heart failure, any persistent arrhythmia or transient serious
arrhythmia (ventricular tachycardia, sinoatrial arrest, etc.), or progressive
cardiomyopathy.

- Unstable blood pressure.

- Seizures or other CNS disorders.

- Severe unstable diabetes mellitus.

- Coagulopathies.

- Thrombotic disease.

- Any other medical conditions that would prevent completion of study or produce
significant risk to patient.

Concurrent Medication:

Excluded:

- Concomitant chemotherapy or immunotherapy.

- Ongoing corticosteroid therapy (unless maintenance).

Patients with the following prior conditions are excluded:

- History of active cardiopulmonary or respiratory disease.

- History of sun hypersensitivity and photosensitive dermatoses.

- History of allergy or hypersensitivity to cosmetics, toiletries, or other
dermatological products.