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Microarray Analysis for Human Genetic Disease


N/A
N/A
N/A
Not Enrolling
Both
Breast Neoplasm, Hereditary Neoplastic Syndrome, Melanoma, Ovarian Neoplasm

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Trial Information

Microarray Analysis for Human Genetic Disease


The purpose of our study is to make use of a novel technology that the Cancer Genetics
Branch of the NHGRI has been a leader in developing. This technology for genome-wide
expression analysis, DNA microarray hybridization, is the focus of our protocol. We will
access tissue banks collected by our collaborators that contain excess tissues obtained
during routine clinical care. Specimens will be processed for large-scale gene expression
analysis and DNA copy number determination using DNA microarrays. The development and
analysis of this gene expression and gene copy number database are the primary purpose of
this study. Currently available and new bioinformatics tools will be applied to the data
for the characterization of disease subsets (e.g., early vs. advanced stage cancer) as well
as to mine the data for specific genes which are linked to given disease states.

Inclusion Criteria


- Clinical inclusion/exclusion criteria will be dependent upon the collaborating
Institutions' requirements.

Type of Study:

Observational

Study Design:

N/A

Authority:

United States: Federal Government

Study ID:

990130

NCT ID:

NCT00001898

Start Date:

June 1999

Completion Date:

May 2008

Related Keywords:

  • Breast Neoplasm
  • Hereditary Neoplastic Syndrome
  • Melanoma
  • Ovarian Neoplasm
  • Melanoma
  • Breast Cancer
  • Gene Expression
  • DNA Chip Technology
  • Expressed Sequence Tags
  • Breast Neoplasms
  • Neoplasms
  • Melanoma
  • Neoplastic Syndromes, Hereditary
  • Ovarian Neoplasms

Name

Location

Johns Hopkins UniversityBaltimore, Maryland  21205
Arizona Cancer CenterTucson, Arizona  85724
University of MichiganAnn Arbor, Michigan  48109-0624
Memorial Sloan Kettering Cancer CenterNew York, New York  10021
MD Anderson Cancer CenterHouston, Texas  77030-4096