Collection of Blood, Bone Marrow and Tissue Samples for the Investigation of the Human Immune Response, Lymphoma Biology and HTLV-1 Infection
- The evaluation of the cells of the immune system and HTLV-1 infection have been a
central focus of the Metabolism Branch for the past 30 years.
- Blood obtained by apheresis or blood drawing, skin biopsies and other tissues will be
evaluated for abnormalities related to immunity, HTLV-1 infection and the immune
- Advances in the characterization of acquired genetic changes in tumor samples has
led to insights for the development of targeted therapy of malignancy
- To define the nature of the immunological, genetic and epigenetic abnormalities in the
cells of patients with immunodeficiency diseases associated with infections and/or a
high incidence of malignancy and in patients with cancer.
- To obtain plasma, leukocytes and skin, lymph node and bone marrow biopsies on patients
with immunodeficiency or cancer to investigate the immune system.
- Subjects with cancer.
- Subjects with immunodeficiency.
- Subjects with HTLV-1 infection.
-This is a natural history study that permits tissue acquisition for analysis of the immune
system and HTLV-1 infection.
Thomas A Waldmann, M.D.
National Cancer Institute (NCI)
United States: Federal Government
|National Institutes of Health Clinical Center, 9000 Rockville Pike||Bethesda, Maryland 20892|